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Margaret L. Rodgers, Ph.D., Stadtman Tenure-Track Investigator
Maggie Rodgers.
Acting Section Chief: Ribonucleoprotein Assembly Section, Laboratory of Biochemistry & Genetics
Scientific Focus Areas: RNA Biology, Biomedical Engineering and Biophysics, Molecular Biology and Biochemistry

Publications

A selection of recent and significant publications can be viewed below.

Ribosomal Protein S12 Hastens Nucleation of Co-Transcriptional Ribosome Assembly.
Rodgers ML, Sun Y, Woodson SA.
Biomolecules (2023 Jun 6) 13. Abstract/Full Text NIH external link
Small RNAs and Hfq capture unfolded RNA target sites during transcription.
Rodgers ML, O'Brien B, Woodson SA.
Mol Cell (2023 May 4) 83:1489-1501.e5. Abstract/Full Text NIH external link
Identification of transient intermediates during spliceosome activation by single molecule fluorescence microscopy.
Fu X, Kaur H, Rodgers ML, Montemayor EJ, Butcher SE, Hoskins AA.
Proc Natl Acad Sci U S A (2022 Nov 29) 119:e2206815119. Abstract/Full Text NIH external link
A roadmap for rRNA folding and assembly during transcription.
Rodgers ML, Woodson SA.
Trends Biochem Sci (2021 Nov) 46:889-901. Abstract/Full Text NIH external link
Transcription Increases the Cooperativity of Ribonucleoprotein Assembly.
Rodgers ML, Woodson SA.
Cell (2019 Nov 27) 179:1370-1381.e12. Abstract/Full Text NIH external link
A newborn RNA switches its fate.
Rodgers ML, Hao Y, Woodson SA.
Nat Chem Biol (2019 Nov) 15:1031-1032. Abstract/Full Text NIH external link
A multi-step model for facilitated unwinding of the yeast U4/U6 RNA duplex.
Rodgers ML, Didychuk AL, Butcher SE, Brow DA, Hoskins AA.
Nucleic Acids Res (2016 Dec 15) 44:10912-10928. Abstract/Full Text NIH external link
Single molecule analysis reveals reversible and irreversible steps during spliceosome activation.
Hoskins AA, Rodgers ML, Friedman LJ, Gelles J, Moore MJ.
Elife (2016 May 31) 5. Abstract/Full Text NIH external link
Structural Analysis of Multi-Helical RNAs by NMR-SAXS/WAXS: Application to the U4/U6 di-snRNA.
Cornilescu G, Didychuk AL, Rodgers ML, Michael LA, Burke JE, Montemayor EJ, Hoskins AA, Butcher SE.
J Mol Biol (2016 Feb 27) 428:777-789. Abstract/Full Text NIH external link
Conformational dynamics of stem II of the U2 snRNA.
Rodgers ML, Tretbar US, Dehaven A, Alwan AA, Luo G, Mast HM, Hoskins AA.
RNA (2016 Feb) 22:225-36. Abstract/Full Text NIH external link
Fluorescent Labeling of Proteins in Whole Cell Extracts for Single-Molecule Imaging.
Hansen SR, Rodgers ML, Hoskins AA.
Methods Enzymol (2016) 581:83-104. Abstract/Full Text NIH external link
Rapid isolation and single-molecule analysis of ribonucleoproteins from cell lysate by SNAP-SiMPull.
Rodgers ML, Paulson J, Hoskins AA.
RNA (2015 May) 21:1031-41. Abstract/Full Text NIH external link
Chemoenzymatic synthesis of bifunctional polyubiquitin substrates for monitoring ubiquitin chain remodeling.
Trang VH, Rodgers ML, Boyle KJ, Hoskins AA, Strieter ER.
Chembiochem (2014 Jul 21) 15:1563-8. Abstract/Full Text NIH external link
Visualizing cellular machines with colocalization single molecule microscopy.
Larson JD, Rodgers ML, Hoskins AA.
Chem Soc Rev (2014 Feb 21) 43:1189-200. Abstract/Full Text NIH external link
Last Reviewed January 2025