Event Details
Agenda
Event Details
Background
Many of our most serious and intractable health problems—including obesity, type 2 diabetes, hypertension, heart disease, and cancer—are linked to what we choose to eat and drink. What we choose to eat and drink is driven largely by the sensory properties of food: taste, smell, and texture. As molecular tools in model organisms become increasingly sophisticated, how can this new information be translated to testable hypotheses to the betterment of human health?
Objectives
- Understand both the hedonic pathways linked to tasting and sensing of food.
- Understand the physiological roles of chemosensory receptors and how these taste and smell sensors are involved in nutrition.
Meeting Co-Chairs
Danielle R. Reed, Ph.D., Monell Chemical Senses Center
Richard D. Mattes, Ph.D., M.P.H., R.D., Purdue University
Organizing Committee
Christopher J. Lynch, Ph.D., National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Susan L. Sullivan, Ph.D., National Institute on Deafness and Other Communication Disorders
Coryse St. Hillaire-Clarke, Ph.D., National Institute on Aging
Padma Maruvada, Ph.D., NIDDK
Registration Deadline
November 1, 2019
Workshop Banner Taste Papilla Image Credit: Dany Gaillard, Ph.D., and Linda Barlow, Ph.D., University of Colorado Anschutz Medical Campus, NIH support from: National Institute on Deafness and Other Communication Disorders (NIDCD)
Agenda
Tuesday, November 12, 2019
- 8:30 a.m. – 8:40 a.m.
- Introduction and Workshop Goals
Christopher Lynch, Ph.D., National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH)
Richard Mattes, Ph.D., M.P.H, RD, Purdue University (Workshop Co-chair)
Danielle Reed, Ph.D., Monell Chemical Senses Center (Workshop Co-chair)
- 8:40 – 8:50 a.m.
- Welcoming Remarks
Griffin P. Rodgers, M.D., MACP, Director, NIDDK, NIH
Session I: Setting the Stage
- 8:50 a.m. – 9:20 a.m.
- Taste Cells, Signals, and Nerves
Nirupa Chaudhari, Ph.D., University of Miami Miller School of Medicine
- 9:20 a.m. – 9:50 a.m.
- Odor Detection in the Olfactory Bulb
John McGann, Ph.D., Rutgers University
- 9:50 a.m. – 10:05 a.m.
- Break
- 10:05 a.m. – 10:35 a.m.
- Central Processing of Taste: Integration of Sensation with Behavior
Alfredo Fontanini, M.D., Ph.D., Stony Brook University
- 10:35 a.m. – 11:05 a.m.
- Reshaping of Sweet Taste by High Dietary Sugar
Monica Dus, Ph.D., University of Michigan
- 11:05 a.m. – 11:50 a.m.
- Session I Panel Discussion
Session I Speakers and Panelists
Panelists: Amber Alhadeff, Ph.D., University of Pennsylvania
John Glendinning, Ph.D., Barnard College, Columbia University
Barry Green, Ph.D., Yale University
Paule Joseph, Ph.D., RN, M.S., FNP-BC, CTN-B, NIH
Timothy Moran, Ph.D., Johns Hopkins University
Kristina Rother, M.D., M.H.Sc., NIH
Alan Spector, Ph.D., Florida State University
- 11:50 a.m. – 12:50 p.m.
- Lunch
Session II: Sensory Nutrition, Public Health, and Disease
- 12:50 p.m. – 1:20 p.m.
- Introduction and Examining Smell and Taste in Large Cohort Studies
Valerie Duffy, Ph.D., RD, University of Connecticut
- 1:20 p.m. – 1:50 p.m.
- Human Cephalic-phase Insulin Response to Nutritive and Low-calorie Sweeteners
Richard Mattes, Ph.D., M.P.H., RD, Purdue University (Workshop Co-chair)
- 1:50 p.m. – 2:20 p.m.
- Personal Differences in Sensory Experience and Human Health
Danielle Reed, Ph.D., Monell Chemical Senses Center (Workshop Co-chair)
- 2:20 p.m. – 2:35 p.m.
- Break
- 2:35 p.m. – 3:05 p.m.
- Early-life Flavor and Sweet Response as It Relates to Cognitive Development and Obesity
Emily Noble, Ph.D., The University of Georgia
- 3:05 p.m. – 3:35 p.m.
- Chemosensory Changes in Obesity and after Metabolic Surgery
M. Yanina Pepino, Ph.D., University of Illinois at Urbana-Champaign
- 3:35 p.m. – 4:05 p.m.
- Hedonic Taste Shifts: Saltiness and Sweetness
Gary Beauchamp, Ph.D., Monell Chemical Senses Center
- 4:05 p.m. – 4:35 p.m.
- Chemosensory Changes in Aging
Claire Murphy, Ph.D., San Diego State University
- 4:35 p.m. – 5:20 p.m.
- Session II Panel Discussion
Session II Speakers and Panelists
- 5:20 p.m.
- Recess
Wednesday, November 13, 2019
Session III: Chemosensation Outside of Traditional Locations
- 8:30 a.m. – 9:00 a.m.
- Chemosensation in Nontraditional Locations—Overview
Jennifer Pluznick, Ph.D., Johns Hopkins University School of Medicine
- 9:00 a.m. – 9:30 a.m.
- Intestinal Bitter Taste Receptor Activation Alters Hormone Secretion and Imparts Metabolic Benefits
Enrique Saez, Ph.D., The Scripps Research Institute
- 9:30 a.m. – 10:00 a.m.
- Sweet Taste Receptors Modulate Glucose Absorption
George Kyriazis, Ph.D., College of Medicine, The Ohio State University
- 10:00 a.m. – 10:30 a.m.
- Effects of Sensory Signaling in the Gastrointestinal Tract on Human Appetite and Food Intake
John McLaughlin, Ph.D., FRCP, The University of Manchester
- 10:30 a.m. – 10:45 a.m.
- Break
- 10:45 a.m. – 11:15 a.m.
- Extra Gustatory Function of Bitter Taste Receptors in the Gut
Catia Sternini, M.D., University of California, Los Angeles
- 11:15 a.m. – 11:45 a.m.
- Microbial Endocrinology: How Evolved Intersections of Microbiology and Neurobiology Matter to Health and Sensory Nutrition
Mark Lyte, Ph.D., M.S., MT(ASCP), Iowa State University
- 11:45 a.m. – 12:30 p.m.
- Round Table Discussion: All Speakers and Panelists
Define the roles that “taste” receptors play in the gut and elsewhere and whether they can be harnessed to improve human health; if so, what are the key technologies and approaches needed for reproducible and high-impact research programs?
- 12:30 p.m.
- Wrap-up and Adjournment