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The goal of this meeting is to encourage scientific exchanges, interactions, and collaborations at the regional level.
Background
The 2023 Annual Mid-Atlantic Diabetes and Obesity Research Symposium is co-organized by the Diabetes, Endocrinology, and Obesity Branch (DEOB) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH); the Perelman School of Medicine at the University of Pennsylvania; University of Maryland School of Medicine and The Johns Hopkins University, School of Medicine.
Organizing Committee
Rebecca Brown
Aaron Cypess
Carol Haft
Connie Noguchi
Marc Reitman
Patrick Seale (Perelman School of Medicine at the University of Pennsylvania)
Arthur Sherman
Simeon Taylor (University of Maryland School of Medicine)
William Wong (The Johns Hopkins University, School of Medicine)
Introductory Remarks
Marc Reitman, M.D., Ph.D., DEOB, NIDDK
Session I
Chair: Rebecca Brown, M.D., M.H.Sc., DEOB, NIDDK
8:30 a.m. – 9:00 a.m.
Invited Talk—Unraveling Disparities in Metformin Responsiveness in Youth-onset Type 2 Diabetes
Stephanie Chung, M.B.B.S., Pediatric Diabetes Section, and Metabolic Clinical Research Unit, DEOB, NIDDK
9:00 a.m. – 9:15 a.m.
Short Talk—The Role of Mitochondrial Copper Transporter, SLC25A3, in Brown Adipose Tissue for Systemic Energy Metabolism
Juyoung Kim, Ph.D., Department of Animal and Avian Sciences, University of Maryland
9:15 a.m. – 9:30 a.m.
Short Talk—State-dependent Prioritization of Feeding and Parenting Behaviors
Ivan Alcantara, M.S., DEOB, NIDDK
9:30 a.m. – 10:00 a.m.
Poster Blitz, Session #1
10:00 a.m. – 10:30 a.m.
Coffee and Posters
10:30 a.m. – 10:35 a.m.
Welcoming Remarks
Griffin P. Rodgers, M.D., MACP, NIDDK
Short Talk—Cannabinoformins for the Treatment of Metabolic Disorders
Malliga Iyer, Ph.D., National Institute on Alcohol Abuse and Alcoholism
10:50 a.m. – 11:20 a.m.
Invited Talk—Fatty Acid Oxidation in Times of Starvation and Plenty
Michael Wolfgang, Ph.D., Department of Biological Chemistry, The Johns Hopkins University School of Medicine
11:20 a.m. – 11:50 a.m.
Poster Blitz, Session #2
11:50 a.m. – 12:20 p.m.
Invited Talk—Novel Molecular Markers of Diabetic Retinopathy
Silvia Montaner, M.Sc., Ph.D., M.P.H., Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland.
12:20 p.m. – 2:00 p.m.
Lunch and Posters
Session III
Chair: William Wong, Ph.D., Physiology Department and Center for Metabolism and Obesity Research, The Johns Hopkins University School of Medicine
2:00 p.m. – 2:30 p.m.
Short Talk—Insulin Signaling through the Insulin Receptor Increases Bone Mineral Density and Linear Growth through Its Effects on Bone in Patients with Severe Insulin Resistance
Rebecca Tuska, NIDDK
2:45 p.m. – 3:15 p.m.
Coffee and Posters
3:15 p.m. – 3:30 p.m.
Short Talk—Dissecting the Molecular Mechanisms by Which Perm1 Enhances Mitochondrial Oxidative Function
Jessica Hernandez, Department of Physiology, The Johns Hopkins University School of Medicine
3:30 p.m. – 3:45 p.m.
Short Talk—Lineage Hierarchy and Transcriptional Regulation of Embryonic Brown Fat Development
Seoyoung Jun, Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania
3:45 p.m. – 4:15 p.m.
Invited Talk—Pancreatic Islet Adaptations During Normal Pregnancy and Defects in Gestational Diabetes
Ron Banerjee, Ph.D., Department of Medicine, Allergy and Immunology Center, The Johns Hopkins University School of Medicine
4:15 p.m.
Adjournment
Blitz Session #1
Padmamalini Baskaran, Ph. D., TRPV1 Activation Antagonizes High-fat Diet-induced Obesity at Thermoneutrality and Enhances UCP-1 Transcription Via PRDM-16
Evangelia Bellas, Ph.D., Microphysiological Modeling of Vascular Adipose Tissue for Multi-Throughput Applications
Scott M. Blackman, Genetic Modifiers of Body Mass Index in Individuals with Cystic Fibrosis
Yang Chen, IRF2BP2 Regulates Hormone Sensitive Lipase and Lipolysis in Human Adipocytes and in Mice
Valerie L. Darcey, Ph.D., M.S., RD., Striatal Dopamine Tone is Positively Associated with Body Mass Index in Humans as Determined by PET Using Dopamine Type-2 Receptor Antagonist Tracers
Ethan C. Fein, MS, Delineating the Developmental Trajectory of Embryonic Brown Fat
Sophia Glaros, BS, TMAO Concentrations in a Randomized Crossover Trial Comparing a Vegan Diet High or Low in Extra Virgin Oil
Aaron Hengist, Ph.D., Discordance Between Postprandial Appetite Hormone Responses and Energy Intake in Humans.
Danielle Lafferty Ph.D., Investigating the Role of GABAergic Projections from the Central Nucleus of the Amygdala to the Parabrachial Nucleus in Food Intake
Liu Liu Ph.D., Regulation of a-cell function by Gs and Gq signaling
Asmita Pramanik Ph.D., Gi-Coupled P2Y14 Receptor Regulates Whole-body Glucose Homeostasis in High Fat Diet-induced Obesity and Type 2 Diabetes
Misbah Rashid, Melanocortin 4 Receptor-mediated Metabolic Effects Require the Presence of b-Arrestin-2 in Specific Neuronal Subpopulations
Mariam S. Sayed, BS., Triglyceride-glucose Index May be a Surrogate for Both Insulin Resistance and Atherogenic Lipid Profile in Black Africans
Vijaya Subramanian, Ph.D., Impact of Alpha- and Beta-cell Dysfunction on the Longitudinal Progression of Type 2 Diabetes (T2D)
Pamela Wax, M.D. MBA, Single Center Retrospective Matched Cohort Study of GLP1RA-induced Weight Loss in Patients With Post-bariatric Weight Regain vs Non-surgical Controls
Blitz Session #2
Jordan Becker, B.S.., A Novel Local Inhibitory Trh to Agrp Circuit That Drives Satiety
Sonum Bharill, M.D., Pediatric Overweight or Obesity is Not Associated with Worst Cardiac Outcomes in Duchenne Muscular Dystrophy
Maiah Brush B.S., The Efficacy of Metreleptin Treatment in Patients with Generalized Lipodystrophy Before vs After the Onset of Significant Metabolic Disease
Aruba Chowdhury B.S., Remnant Lipoprotein Particles and Cholesterol Contribute to Proatherogenic Phenotype and Subclinical Inflammation in Youth-Onset Type 2 Diabetes
Isabel de Araujo Salgado, Toggling Between Food-Seeking and Self-Preservation Behaviors Via Hypothalamic Response Networks
Claire Gao, Ph.D., The Role of Parabrachial Nucleus in Semaglutide-Mediated Regulation of Appetite
Joon Ha, Ph.D., The Most Common Pathway to T2D in Lean Koreans
Injae Hwang Ph.D., Understanding the Dynamic Role of Ketone Body Metabolism in the Regulation of Adipose Tissue Inflammation and Insulin Resistance
Daniel Lank MS., Postprandial Increase of Adenosine 2B Receptor in Adipose Tissue Increases Propensity for Lipolysis
Lin Liu, T2D-Associated Gene VPS11 Controls Human Muscle Cell Differentiation via Regulation of Iron Availability and Inflammation
Sam Preza, BS., Designer Islets: Improving SC-islet In-vitro Performance Through Beta-Cell Enrichment
Oleta A. Sandiford., Short-term High-fat Diet Impairs Norepinephrine-dependent Ca2+ Signaling in Hepatocytes and the Intact Liver
Megan Stefkovich, Acute Control of Hepatic Glucose Uptake and Utilization by Insulin.
Umesh D. Wankhade, Maternal High-fat Diet-induced Obesity in Offspring: Unraveling Adipose Tissue Dysfunction Mediated by Increased Heat Shock Proteins
Jaclyn E. Welles, Investigating the Role of Phosphatidylcholine in NASH-associated Fibrosis and Inflammation
Abstracts
Submission Deadline
August 31, 2023
Submitting Abstracts
Participants in the 2023 Mid-Atlantic Diabetes and Obesity Research Symposium are encouraged to submit poster abstracts. You must register for the Symposium in order to submit an abstract. A small number of abstracts will be chosen for a “hot topic” (10-minute) oral presentation. The remaining abstracts will be scheduled for a 2-minute blitz presentation in addition to poster presentation. All posters and short talk will be in-person only.
All abstracts must be submitted via email to Janiya Peters of The Scientific Consulting Group, Inc., with “Mid-Atlantic Abstract” in the subject line. Abstract submissions should be no longer than 250 words (not including name and affiliation). Please make sure to read the formatting requirements below very carefully. It is extremely important that you follow these specifications.
Formatting Requirements
The abstract should be an MS Word document, typed and single-spaced using Times New Roman font. Everything but the title should be in normal, 12-point font.
The abstract’s title should be Bold, 16-Point, Title Case font and should clearly represent the nature of the investigation.
On the first line after the title, list the authors’ first and last names, degree, affiliation, city, state, and country.
Separate multiple authors with a semicolon and underline the primary author’s name (one primary author per abstract).
Primary author’s email address must be included under the list of author’s.
Use one blank line between the title and the body of the abstract and between paragraphs.
The abstract file name should follow this format: primary author’s LastName_FirstWordOfTitle (e.g., Zucker_Effects).
Please ensure that your abstract is the correct length (250 words or less) and use 1-inch margins.
The use of standard abbreviations is desirable (e.g., RBC), as well as standard symbols for units of measure (e.g., kg, g, mg, mL, L, and %). Place nonstandard or unusual abbreviations within parentheses after the full word the first time that it appears. Use numerals to indicate numbers, except to begin sentences. Do not use subtitles (e.g., Methods, Results).
Simple tables or graphs may be included; however, they must fit within the designated abstract space of one page.
Organize the body of the abstract as follows:
Statement of the purpose of the study/program/project
Statement of the methods used
Summary of the results presented in sufficient detail to support the conclusion
Statement of the conclusions reached
Event Logistics
Registration
Registration Closed
Registration ended
Location
Natcher Conference Center Building 45, NIH Bethesda,MD20892