Section on mRNA Regulation & Translation

of the Laboratory of Biochemistry & Genetics

A group of scientists interested in the mechanism of the ribosome and how changes in translation alter gene expression in diseases.

Select Publications

Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response.
Karasik A, Lorenzi HA, DePass AV, Guydosh NR.
Cell Rep (2024 Jun 25) 43:114287. Abstract/Full Text
The ubiquitin conjugase Rad6 mediates ribosome pausing during oxidative stress.
Meydan S, Barros GC, Simões V, Harley L, Cizubu BK, Guydosh NR, Silva GM.
Cell Rep (2023 Nov 28) 42:113359. Abstract/Full Text
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Last Reviewed January 2024