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NIH: National Institute of Diabetes and Digestive and Kidney Diseases NIH: National Institute of Diabetes and Digestive and Kidney Diseases 75 years: 1950-2025 75 years: 1950-2025
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Single-Molecule Biophysics Section
Section Chief: Hoi Sung Chung, Ph.D.

Software & Data

FRET_3colorCW
Maximum likelihood analysis of 3-color FRET photon trajectories generated by continuous-wave donor excitation.
Nat Commun 11 3336 (2020)

FNet
A neural network designed for intensity-based separation of overlapping transparent objects using temporal information of a sequence of images. It was developed for the analysis of the growth of amyloid-beta fibrils, but can also be used for separation of any arbitrary objects.
PNAS 119 e2116736119 (2022)

FRET_burstML
Maximum likelihood analysis of 2- and 3-color photon trajectories of fluorescence bursts from freely diffusing molecules.
J Phys Chem B 129 2187 (2025)

Last Reviewed April 2025