Studying epigenomic regulation of cell differentiation, with a focus on enhancer regulation by histone modifying or chromatin remodeling enzymes
Select Publications
- KMT2 Family of H3K4 Methyltransferases: Enzymatic Activity-dependent and -independent Functions.
- Van HT, Xie G, Dong P, Liu Z, Ge K.
- J Mol Biol (2024 Apr 1) 436:168453. Abstract/Full Text
- ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
- Zhang Y, Xie G, Lee JE, Zandian M, Sudarshan D, Estavoyer B, Benz C, Viita T, Asgaritarghi G, Lachance C, Messmer C, Simonetti L, Sinha VK, Lambert JP, Chen YW, Wang SP, Ivarsson Y, Affar EB, Côté J, Ge K, Kutateladze TG.
- Nat Commun (2024 Jun 7) 15:4883. Abstract/Full Text
Lab Members
Back left to right: Guojia Xie, Young-Kwon Park, Christabelle Agyapong, Hieu Van. Front left to right: Kai Ge, Cuncun Ke, Danyang Wan, Ji-Eun Lee.
Last Reviewed May 2024