Conducting translational and basic studies on immune responses to viruses, in particular those that affect the liver, and their regulation by the gastrointestinal microbiome.

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Neonatal exposure to a wild-derived microbiome protects mice against diet-induced obesity.
Hild B, Dreier MS, Oh JH, McCulloch JA, Badger JH, Guo J, Thefaine CE, Umarova R, Hall KD, Gavrilova O, Rosshart SP, Trinchieri G, Rehermann B.
Nat Metab (2021 Aug) 3:1042-1057. Abstract/Full Text
Laboratory mice born to wild mice have natural microbiota and model human immune responses.
Rosshart SP, Herz J, Vassallo BG, Hunter A, Wall MK, Badger JH, McCulloch JA, Anastasakis DG, Sarshad AA, Leonardi I, Collins N, Blatter JA, Han SJ, Tamoutounour S, Potapova S, Foster St Claire MB, Yuan W, Sen SK, Dreier MS, Hild B, Hafner M, Wang D, Iliev ID, Belkaid Y, Trinchieri G, Rehermann B.
Science (2019 Aug 2) 365. Abstract/Full Text
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Lab Members

Immunology Section in front of National Institutes of Health Building 1 on September 20, 2024. From left to right: Alexis Moore, Keisuke Fukutomi, Sabitree Shahi, Shahar Azar, Barbara Rehermann, Ji Hoon Oh, Jun Seishima.

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Last Reviewed October 2024