Research Materials & Patents
Patents, materials, and other research resources appear below. Some resources may be available for use through Material Transfer Agreements (MTAs) or licensing agreements.
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Alb-tTA (Tg(Alb1-tTA)3123Lng) Mouse
Tetracycline-responsive transcriptional activator driven by the liver-specific mouse albumin promoter (Alb-tTA). The E. Coli tetracycline operon regulatory system was used to generate a liver-specific transcription activation system that was… -
Method of detecting antigenic, nucleic acid-containing macromolecular entities (U.S. Patent Number 5,077,192)
A method for the detection of nucleic acid-containing moieties is described which combines affinity capture of the moiety with detection and identification of the moiety's nucleic acid -
Methods of preventing viral replication (U.S. Patent Number 5,610,050)
The invention relates to methods and compositions for inhibition of viral replication. In particular, termination of replication of hepatitis B virus is achieved by introducing into a target cell an antisense oligonucleotide having a sequence… -
MUP-tTA Mouse
Tetracycline-responsive transcriptional activator driven by the liver-specific mouse major urinary protein promoter (MUP-tTA).The E. Coli tetracycline operon regulatory system was used to generate a liver-specific transcription activation system that… -
Synthesis & purification of hepatitis C virus-like particles (U.S. Patent Number 6,387,662)
Production of enveloped RNA virus-like particles intracellularly in vitro in insect cells using a recombinant baculovirus vector containing a cDNA coding for viral structural proteins is disclosed. In vitro production and purification of hepatitis C…