Single Source for the Continuation of the Type 1 Diabetes in Acute Pancreatitis Consortium - Data Coordinating Center (T1DAPC-DCC) (U01 Clinical Trial Optional)

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is announcing its intent to request a single source cooperative agreement application from the Pennsylvania State University Hershey Medical Center for the continuation of the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC), a clinical consortium composed of one Data Coordinating Center (DCC) and up to ten Clinical Centers (CC) to continue a prospective longitudinal observational study of the incidence of diabetes that occurs during or after an acute pancreatitis (AP) episode, with an emphasis on type 1 diabetes (T1D) [the Diabetes Related to Acute Pancreatitis and its Mechanisms (DREAM) study] (NCT05197920). The study has been designed to gain insight into the incidence, clinical evolution, etiology, type, and pathophysiology of T1D and other forms of diabetes that occur during, or after one or more episodes of AP. The Pennsylvania State University Hershey Medical Center serves as the DCC of the currently funded consortium and has been instrumental in providing all the administrative, regulatory, managerial, logistic, analytic and financial functions to establish and pursue the research objectives of the T1DAPC.

Applications for the CCs can be submitted in response to a separate NOFO, RFA-DK-25-017: Limited Competition for the Continuation of the Type 1 Diabetes in Acute Pancreatitis Consortium Clinical Centers (T1DAPC-CC) (U01 Clinical Trial Optional).

Key Dates

Open Date: 10/21/2024

Letter of Intent Due Date: October 21, 2024

Application Due Date: November 19, 2024