Novel Software Tools to Identify New Pathways of Blood Disease Development using Existing Genomic Datasets

May 2022 Council

Lead Division/Office

KUH

Point(s) of Contact

Shilpa Hattangadi, M.D.; Cindy Roy, Ph.D.

Executive Summary

The purpose of this funding opportunity is to combine access to existing patient datasets and developmental ‘omic resources with innovative, more widely-applicable, software tools for identification of novel disease pathways, especially in non-malignant hematologic diseases. We expect the development of new software tools for genotype-phenotype analyses and disease pathway identification will provide junior investigators without current preliminary data unique opportunities to develop independent research areas in novel pathways elucidated from these datasets. We propose an initial biohackathon to build some of these software tools the year before the grant opportunity, to introduce data scientists to the hematology community, and to foster a hematology data science community.