Post-Dialysis Fatigue and Patient Science

May 2024 Council

Lead Division/Office

KUH

Point(s) of Contact

Kevin Chan, M.D.

Executive Summary

Most people on chronic dialysis develop debilitating fatigue after their dialysis treatment. The scientific literature of post-dialysis fatigue is sparse and we lack  basic diagnostic criteria, an outcome measure, and pathophysiological explanation for this disease. This cooperative research initiative proposes to engage people with post-dialysis fatigue with qualitative scientists to establish a robust case definition, a diagnostic instrument, an outcome measure, and quality metrics for post-dialysis fatigue. The epidemiology and biology of the disease will be defined. This foundational science will form an anchor for subsequent therapy development and clinical trials.