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NIH: National Institute of Diabetes and Digestive and Kidney Diseases NIH: National Institute of Diabetes and Digestive and Kidney Diseases 75 years: 1950-2025 75 years: 1950-2025
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Section of Genetics & Physiology

of the Laboratory of Cell & Molecular Biology

Lothar Hennighausen. Lothar Hennighausen, Ph.D.

Section Chief

lotharh@mail.nih.gov
Our long-term goal is to unlock the genetic logic that controls the genome and to understand the impact of single nucleotide polymorphisms (SNPs) in the Janus Kinase-Signal Transducer and Activator of Transcription (JAK-STAT) pathway contributing to autoimmune disease to support design of therapeutic interventions.
About Our Research

Select Publications

Cell-specific and shared regulatory elements control a multigene locus active in mammary and salivary glands.
Lee HK, Willi M, Liu C, Hennighausen L.
Nat Commun (2023 Aug 17) 14:4992. Abstract/Full Text
mRNA vaccination in octogenarians 15 and 20 months after recovery from COVID-19 elicits robust immune and antibody responses that include Omicron.
Lee HK, Knabl L, Moliva JI, Knabl L Sr, Werner AP, Boyoglu-Barnum S, Kapferer S, Pateter B, Walter M, Sullivan NJ, Furth PA, Hennighausen L.
Cell Rep (2022 Apr 12) 39:110680. Abstract/Full Text
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Lab Members Research Materials
Last Reviewed March 2025