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Metabolism, Energy Balance & Obesity

Basic and clinical studies related to energy balance and physiological mechanisms modulating weight gain, loss and maintenance.

NIDDK Program Staff

  • Brad Cooke, Ph.D. Developmental Neuroendocrinology, Electrophysiology, and Cognitive Neuroscience
  • Diana Cummings, Ph.D. Gut-Brain Interactions in Nutrition and Obesity; Nutrient Sensing; Gastrointestinal Interoception; Neurobiology of Nausea and Vomiting
  • Dhananjay (Jay) Gupta, Ph.D., M.S. Basic research on pathogenesis of obesity and Type 2 Diabetes; Role of gene-environment interaction in regulation of metabolism; Transcriptional regulation of gene expression; Cellular signaling pathways regulating intermediary metabolism and cellular identity
  • Carol Renfrew Haft, Ph.D. Adipocyte development and biology in various fat depots; protein trafficking, secretion, processing and ER stress in metabolic disease
  • Maren Laughlin, Ph.D. Energy balance, thermogenesis and mitochondria biology, lipid metabolism, and functional and metabolic imaging in adipose, pancreas and other metabolic organs.
  • Hanyu Liang, M.D., Ph.D. Hepatic Metabolism; Insulin Resistance; Type 2 Diabetes; Obesity; Bariatric Surgery
  • Padma Maruvada, Ph.D. Nutrient Metabolism; Clinical Obesity and Nutrition
  • Corinne M. Silva, Ph.D. Circadian rhythms, Metabolic Signaling Pathways, Clock Protein Role in Gene Expression, Diabetes, Obesity
  • Xujing Wang, Ph.D. Data science and artificial intelligence (AI); computation modeling; integrative genomics; network biology; genotype-phenotype relationship

Recent Funding Opportunities

View More Recent Funding Opportunities
  1. PAR-25-090

    NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34 Clinical Trial Optional)

  2. PAR-25-091

    Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

  3. PAR-25-312

    Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed)

  4. PAS-25-073

    Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)

  5. PAS-25-102

    Small R01s for Clinical Trials Targeting Diseases within the Mission of NIDDK (R01 Clinical Trial Required)

View More Recent Funding Opportunities
  • View related clinical trials from ClinicalTrials.gov.

  • NIH Study Sections NIH external link

    Study sections conduct initial peer review of applications in a designated scientific area. Visit the NIH’s Center for Scientific Review website to search for study sections.


Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

Additional Research Programs

 Research TrainingSmall BusinessHuman Subjects ResearchTranslational Research 
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NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.

Learn about NIDDK Research Training Programs

Meetings & Workshops

  • NIH Common Fund

    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund NIH external link.

  • Planning to Apply? Register Early

    Registration is required at eRA Commons NIH external link and grants.gov External link and can take 4 weeks.

Last Reviewed October 2024