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Pathophysiology of Diabetes & Metabolic Disease

Basic and clinical research that addresses the pathophysiology of metabolic diseases, including type 1 and type 2 diabetes.

NIDDK Program Staff

  • Kristin M. Abraham, Ph.D. Development of resources and infrastructure to support provision and exploration of human tissues for studies of diabetes, and improvements in innovative mouse models to advance diabetes research.
  • Guillermo A. Arreaza-Rubín, M.D. Diabetes and endocrine disease bioengineering and glucose sensing
  • Rajatava Basu, Ph.D. Role of immune system in the pathophysiology of Type 2 Diabetes and diabetes-associated metabolic dysfunction, including the role of chronic & meta-inflammation, microbiome-immune-metabolic crosstalk and neuroinflammation
  • Olivier Blondel, Ph.D. Pathophysiology of the endocrine pancreas in diabetes; technology development (i.e. genomics and systems biology) in metabolic disease
  • Miranda Broadney, M.D., M.P.H. Pediatrics, Pediatric Endocrinology, Clinical Management of Diabetes Mellitus, Insulin Resistance, Pediatric Obesity
  • Maren Laughlin, Ph.D. Energy balance, thermogenesis and mitochondria biology, lipid metabolism, and functional and metabolic imaging in adipose, pancreas and other metabolic organs.
  • Hanyu Liang, M.D., Ph.D. Hepatic Metabolism; Insulin Resistance; Type 2 Diabetes; Obesity; Bariatric Surgery
  • Barbara Linder, M.D., Ph.D. Type 2 diabetes in children and youth; human studies of metabolic imprinting
  • Corinne M. Silva, Ph.D. Circadian rhythms, Metabolic Signaling Pathways, Clock Protein Role in Gene Expression, Diabetes, Obesity

Recent Funding Opportunities

View More Recent Funding Opportunities
  1. PAR-25-090

    NIDDK High Risk Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34 Clinical Trial Optional)

  2. PAR-25-091

    Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

  3. PAR-25-312

    Time-Sensitive Evaluation of Policies Affecting Health Behaviors and Chronic Disease Risk (R01-Clinical Trial Not Allowed)

  4. PAS-25-073

    Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)

  5. PAS-25-102

    Small R01s for Clinical Trials Targeting Diseases within the Mission of NIDDK (R01 Clinical Trial Required)

View More Recent Funding Opportunities

Research Resources

NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

Additional Research Programs

 Research TrainingSmall BusinessHuman Subjects ResearchTranslational Research 
Funding Eligibility by Career Level arrow graphic

NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.

Learn about NIDDK Research Training Programs

Meetings & Workshops

  • NIH Common Fund

    Learn about current projects and view funding opportunities sponsored by the NIH Common Fund NIH external link.

  • Planning to Apply? Register Early

    Registration is required at eRA Commons NIH external link and grants.gov External link and can take 4 weeks.

Last Reviewed October 2024